Pyoderma Gangrenosum: A Challenging Cutaneous Manifestation in Dubowitz Syndrome
نویسندگان
چکیده
Pyoderma gangrenosum (PG) is a challenging cutaneous manifestation associated with Dubowitz syndrome, rare genetic disorder characterized by multiple congenital anomalies, developmental delay, and distinctive facial features. This review article aims to provide comprehensive overview of the association between syndrome pyoderma gangrenosum, emphasizing clinical presentation, challenges in diagnosis management, potential underlying mechanisms. A literature search was conducted gather relevant studies, inclusion exclusion criteria were applied select appropriate articles. The has been documented reported cases studies. Clinical characteristics include painful necrotic ulcers undermined borders. Diagnosing context can be due overlapping features complexities syndrome. Managing involves multidisciplinary approach, general principles wound care, systemic therapy, pain management. Specific considerations for treating collaboration among specialists careful monitoring. Future directions management further research understand mechanisms develop targeted therapies. Recognizing addressing crucial optimal patient care. enhances awareness healthcare professionals provides insights improving diagnosis, treatment outcomes individuals this combination conditions.
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ژورنال
عنوان ژورنال: Cureus
سال: 2023
ISSN: ['2168-8184']
DOI: https://doi.org/10.7759/cureus.43408